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Journal Article 29

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2023 1

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2019 3

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CD14 2

adult 2

allogeneic hematopoietic stem cell transplantation 2

imatinib 2

liver transplantation 2

Triticum aestivum 1

Adult rats 1

B lymphocytes 1

Bu-Fei Jian-Pi granules 1

Bu-Fei Yi-Shen granules 1

CALLG2008 1

Cynoglossus semilaevis Günther； recirculating aquaculture； stocking density； growth； nutrient composition 1

EM/PM subtyping 1

Growth performance 1

Leucine 1

Low-protein diet 1

Muscle weight 1

October 1

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Muscle Weight and Postprandial Protein Synthesis of Skeletal Muscle by Promoting the mTOR Pathway in AdultRats

Bo Zhang, Licui Chu, Hong Liu, Chunyuan Xie, Shiyan Qiao, Xiangfang Zeng

Engineering 2017, Volume 3, Issue 5,   Pages 760-765 doi: 10.1016/J.ENG.2017.03.008

Abstract: investigate whether leucine supplementation would increase the synthesis rate of protein and muscle weight in adultrats, which chronically consume only 58.8% of their protein requirements.Thirty-six male Sprague-Dawley rats were assigned to one of three dietary treatments including a 20%In conclusion, when protein is chronically restricted in adult rat diets, leucine supplementation moderately

Keywords： Low-protein diet     Leucine     Growth performance     Muscle weight     Protein synthesis     Adult rats    

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Reducing biliary complications in adult-to-adult living donor liver transplantation using right lobe

YAN Lunan, WEN Tianfu, WANG Wentao, YANG Jiayin, XU Mingqing, CHEN Zheyu, WU Hong

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 130-133 doi: 10.1007/s11684-008-0024-z

Abstract: is to summarize our experience of using right lobe liver grafts to reduce biliary complications in adult-to-adultFrom January 2002 to October 2007, 124 adult patients underwent living donor liver transplantation using

Keywords： microsurgical     October     improved     success     transplantation    

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Advances in immunopathogenesis of adult immune thrombocytopenia

Xinguang Liu, Yu Hou, Jun Peng

Frontiers of Medicine 2013, Volume 7, Issue 4,   Pages 418-424 doi: 10.1007/s11684-013-0297-8

Abstract:

Primary immune thrombocytopenia (ITP) is an autoimmune disorder characterized by immune-mediated accelerated platelet destruction and/or suppressed platelet production. Although the development of autoantibodies against platelet glycoproteins remains central in the pathophysiology of ITP, several abnormalities involving the cellular mechanisms of immune modulation have been identified, and the pathways behind the immune-mediated destruction of platelets have opened new avenues for the design of specific immunotherapies in an attempt to reduce the platelet destruction. This review is primarily focused on the recent literature with respect to immunopathological mechanisms in patients with ITP.

Keywords： primary immune thrombocytopenia     B lymphocytes     T lymphocytes     antigen-presenting cells     cytokines    

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Preliminary experience in adult-to-adult living donor liver transplantation in a single center in China

YAN Lunan, ZENG Yong, WEN Tianfu, ZHAO Jichun, WANG Wentao, YANG Jiayin, XU Mingqing, MA Yukui, CHEN Zheyu, LIU Jiangwen, WU Hong

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 136-141 doi: 10.1007/s11684-007-0026-2

Abstract: The aim of this paper is to report the authors experience in performing adult-to-adult living donorFrom January 2002 to September 2006, 56 adult patients underwent LDLT using right lobe grafts at the
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of RNA interference targeting angiotensin 1a receptor on blood pressure and cardiac hypertrophy of rats

ZHANG Jingqun, SUN Honglei, MA Yexin, WANG Daowen

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 19-24 doi: 10.1007/s11684-008-0005-2

Abstract: interference (RNAi) targeting angiotensin 1a receptor (AT1a) on blood pressure and cardiac hypertrophy of ratsThirty Sprague – Dawley rats with renovascular hypertension (2-kidney 1-clip) were randomly divided intoThe ratio of left ventricle weight to body weight (LV/BW) of the rats in pAT1a-shRNA1, pAT1a-shRNA2,groups decreased significantly than in the control group ( < 0.01), similar to those of the normal SD rats

Keywords： therapy     Sprague     administration     cardiac hypertrophy     valsartan    

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mononuclear diploid cardiac subpopulation with minimal cell–cell communications persists in embryonic and adult

Frontiers of Medicine   Pages 939-956 doi: 10.1007/s11684-023-0987-9

Abstract: proportion of mononuclear diploid cardiomyocytes (MNDCMs), with regeneration potential, could persist in adultthe Myl4+Tnni1+ MNDCMs persisted in embryonic and adult

Keywords： mononuclear diploid cardiomyocytes     cell–cell communication     cardiac fibroblast     single-cell RNA sequencing     cardiac regeneration    

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Genetic basis of adult-onset nephrotic syndrome and focal segmental glomerulosclerosis

Jian Liu, Weiming Wang

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 333-339 doi: 10.1007/s11684-017-0564-1

Abstract: Adult-onset FSGS/NS is often associated with low response to steroid treatment and immunosuppressiveIn this review, we focus on the recently identified genes in the adult-onset NS and FSGS and discuss

Keywords： nephrotic syndrome     focal segmental glomerulosclerosis     genetic    

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Temporal and spatial stability of the EM/PM molecular subtypes in adult diffuse glioma

Frontiers of Medicine 2023, Volume 17, Issue 2,   Pages 240-262 doi: 10.1007/s11684-022-0936-z

Abstract: Detailed characterizations of genomic alterations have not identified subtype-specific vulnerabilities in adultco-expressed with EGFR or PDGFRA (EM or PM), we recently proposed an EM/PM classification scheme for adultThus, while genetic makeup may change during progression and/or within different tumor areas, adult gliomas

Keywords： glioma progression     molecular classification     EM/PM subtyping     intratumor heterogeneity    

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Effect of Feixian Recipe on laminin, collagen I and III in rats with pulmonary fibrosis induced by bleomycin

ZHANG Xiaomei, JIANG Liangduo, ZHANG Wei, WU Jianjun, LU Xiangfeng

Frontiers of Medicine 2008, Volume 2, Issue 3,   Pages 314-316 doi: 10.1007/s11684-008-0060-8

Abstract: The aim of this paper is to observe the effect of the Feixian Recipe on pulmonary fibrosis in rats.Feixian Recipe has a significant therapeutic effect on bleomycin-induced pulmonary fibrosis in rats.

Keywords： bleomycin     intratracheal injection     prednisone     collagen     bleomycin-induced pulmonary    

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Structural shifts in the intestinal microbiota of rats treated with cyclosporine A after orthotropic

Junjun Jia, Xinyao Tian, Jianwen Jiang, Zhigang Ren, Haifeng Lu, Ning He, Haiyang Xie, Lin Zhou, Shusen Zheng

Frontiers of Medicine 2019, Volume 13, Issue 4,   Pages 451-460 doi: 10.1007/s11684-018-0675-3

Abstract: Understanding the effect of immunosuppressive agents on intestinal microbiota is important to reduce the mortality and morbidity from orthotopic liver transplantation (OLT). We investigated the relationship between the commonly used immunosuppressive agent cyclosporine A (CSA) and the intestinal microbial variation in an OLT model. The rat samples were divided as follows: (1) N group (normal control); (2) I group (isograft LT, Brown Norway [BN] rat to BN); (3) R group (allograft LT, Lewis to BN rat); and (4) CSA group (R group treated with CSA). The intestinal microbiota was assayed by denaturing gradient gel electrophoresis profiles and by using real-time polymerase chain reaction. The liver histopathology and the alanine/aspartate aminotransferase ratio after LT were both ameliorated by CSA. In the CSA group, the numbers of rDNA gene copies of cluster I, cluster XIV, and Enterobacteriaceae decreased, whereas those of increased compared with the R group. Cluster analysis indicated that the samples from the N, I, and CSA groups were clustered, whereas the other clusters contained the samples from the R group. Hence, CSA ameliorates hepatic graft injury and partially restores gut microbiota following LT, and these may benefit hepatic graft rejection.

Keywords： microbial community     liver transplantation     immunosuppressive agents     cyclosporine A    

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Alleviation of cell damage in experimental ANP in rats by administration of chondroitin-sulfate reduces

HE Zhongye, GUO Renxuan, LI Yang, XIE Chengyao, LIU Nan, SONG Wen

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 36-40 doi: 10.1007/s11684-007-0007-5

Abstract: cytoprotection and attenuation of oxidative damage during acute necrotic pancreatitis (ANP), male Wistar ratsThe rats in group A was subjected to retrograde injection of 5% sodium taurocholate via the pancreaticAll rats in three groups were killed at 6 h.

Keywords： control     Wistar     taurocholate     superoxide dismutase     chondroitin-sulfate therapy    

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Sensory innervation of the anterior eye segment in rats: a retrograde tracing study

Haixia LIU MD , Zhiwang LI MD , Min YANG MD , Xiang TIAN MS , Chaoying LI PhD , Lei PEI PhD ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 352-356 doi: 10.1007/s11684-009-0065-y

Abstract: This study aimed to investigate the sensory innervation of the anterior eye segment in rats by retrograde

Keywords： trigeminal ganglion     retrograde tracing    

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of beta-elemene on the levels of plasma endotoxin, serum TNF-alpha, and hepatic CD14 expression in rats

Jianguo LIU, Zhe ZHANG, Jiechang GAO, Jiwen XIE, Lin YANG, Shenjun HU

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 101-105 doi: 10.1007/s11684-011-0111-4

Abstract: experimental model was induced by the hypodermical injection of CCl4 in Wistar male ratsβ-elemene was intraperitoneally administered into rats for 8 weeks (0.1 mL/100 g bodyweight percan downregulate the levels of plasma endotoxins, serum TNF-α, and hepatic CD14 expression in rats

Keywords： liver fibrosis     beta-elemene     endotoxin     CD14    

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Emergency adult living donor right lobe liver transplantation for fulminant hepatic failure

ZHANG Feng, WANG Xuehao, LI Xiangcheng, KONG Lianbao, SUN Beicheng, LI Guoqiang, QIAN Xiaofen, CHEN Feng, WANG Ke, LU Sheng, PU Liyong, LU Ling

Frontiers of Medicine 2007, Volume 1, Issue 3,   Pages 282-286 doi: 10.1007/s11684-007-0054-y

Abstract: Nine cases of adult right lobe LDLT were performed in our department from September 2002 to August 2005Emergency adult living-donor liver transplantation is an effective treatment for fulminant hepatitis

Keywords： alimentary     abnormal     hemorrhage     principal     different    

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Efficacy and prognostic factors of imatinib plus CALLG2008 protocol in adult patients with newly diagnosed

Yinjun Lou, Yafang Ma, Chenyin Li, Sansan Suo, Hongyan Tong, Wenbin Qian, Wenyuan Mai, Haitao Meng, Wenjuan Yu, Liping Mao, Juyin Wei, Weilei Xu, Jie Jin

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 229-238 doi: 10.1007/s11684-017-0506-y

Abstract: CALLG2008 protocol was developed by the Chinese Acute Lymphoblastic Leukemia Cooperative Group for adultWe retrospectively analyzed 153 newly diagnosed adult patients with Philadelphia chromosome (Ph)-positive

Keywords： Philadelphia chromosome     acute lymphoblastic leukemia     imatinib     CALLG2008    

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Title Author Date Type Operation

Muscle Weight and Postprandial Protein Synthesis of Skeletal Muscle by Promoting the mTOR Pathway in AdultRats

Bo Zhang, Licui Chu, Hong Liu, Chunyuan Xie, Shiyan Qiao, Xiangfang Zeng

Journal Article

Reducing biliary complications in adult-to-adult living donor liver transplantation using right lobe

YAN Lunan, WEN Tianfu, WANG Wentao, YANG Jiayin, XU Mingqing, CHEN Zheyu, WU Hong

Journal Article

Advances in immunopathogenesis of adult immune thrombocytopenia

Xinguang Liu, Yu Hou, Jun Peng

Journal Article

Preliminary experience in adult-to-adult living donor liver transplantation in a single center in China

YAN Lunan, ZENG Yong, WEN Tianfu, ZHAO Jichun, WANG Wentao, YANG Jiayin, XU Mingqing, MA Yukui, CHEN Zheyu, LIU Jiangwen, WU Hong

Journal Article

of RNA interference targeting angiotensin 1a receptor on blood pressure and cardiac hypertrophy of rats

ZHANG Jingqun, SUN Honglei, MA Yexin, WANG Daowen

Journal Article

mononuclear diploid cardiac subpopulation with minimal cell–cell communications persists in embryonic and adult

Journal Article

Genetic basis of adult-onset nephrotic syndrome and focal segmental glomerulosclerosis

Jian Liu, Weiming Wang

Journal Article

Temporal and spatial stability of the EM/PM molecular subtypes in adult diffuse glioma

Journal Article

Effect of Feixian Recipe on laminin, collagen I and III in rats with pulmonary fibrosis induced by bleomycin

ZHANG Xiaomei, JIANG Liangduo, ZHANG Wei, WU Jianjun, LU Xiangfeng

Journal Article

Structural shifts in the intestinal microbiota of rats treated with cyclosporine A after orthotropic

Junjun Jia, Xinyao Tian, Jianwen Jiang, Zhigang Ren, Haifeng Lu, Ning He, Haiyang Xie, Lin Zhou, Shusen Zheng

Journal Article

Alleviation of cell damage in experimental ANP in rats by administration of chondroitin-sulfate reduces

HE Zhongye, GUO Renxuan, LI Yang, XIE Chengyao, LIU Nan, SONG Wen

Journal Article

Sensory innervation of the anterior eye segment in rats: a retrograde tracing study

Haixia LIU MD , Zhiwang LI MD , Min YANG MD , Xiang TIAN MS , Chaoying LI PhD , Lei PEI PhD ,

Journal Article

of beta-elemene on the levels of plasma endotoxin, serum TNF-alpha, and hepatic CD14 expression in rats

Jianguo LIU, Zhe ZHANG, Jiechang GAO, Jiwen XIE, Lin YANG, Shenjun HU

Journal Article

Emergency adult living donor right lobe liver transplantation for fulminant hepatic failure

ZHANG Feng, WANG Xuehao, LI Xiangcheng, KONG Lianbao, SUN Beicheng, LI Guoqiang, QIAN Xiaofen, CHEN Feng, WANG Ke, LU Sheng, PU Liyong, LU Ling

Journal Article

Efficacy and prognostic factors of imatinib plus CALLG2008 protocol in adult patients with newly diagnosed

Yinjun Lou, Yafang Ma, Chenyin Li, Sansan Suo, Hongyan Tong, Wenbin Qian, Wenyuan Mai, Haitao Meng, Wenjuan Yu, Liping Mao, Juyin Wei, Weilei Xu, Jie Jin

Journal Article